The cryo-EM structure of the GAPM complex: the bridge between the gliding machinery and the cytoskeleton in the malaria parasite

Clinton Lau studies how cytoskeletal filament systems position and shape organelles within parasite cells. Using structural methods (cryo-EM), biochemical assays (single-molecule TIRF microscopy), mass spectrometry, and CRISPR/Cas9 gene editing, they investigate the structure, function, and interaction networks of these proteins. More information >